Acumulado Enero - Diciembre 2022 (93 - 96) N°93
DOI:10.70024 / ISSN 1317-987X
Artículos
 
Ensayo
Referencias



Asociación Venezolana para el Avance de la Ciencia
De la mitocondria a los parásitos: un viaje con muchos intervalos

Referencias

  1. González-Cadavid, N.F., Avila-Bello, E. y Ramírez, J.L. "Differential long term effects of D-chloramphenicol in the biogenesis of mitochondria, in normal and regenerating rat liver.  Biochem. J. (1970) 118:577-586.
  2. Cohen, S. N., Chang, A. C., Boyer, H. W., & Helling, R. B. Construction of biologically functional bacterial plasmids in vitro. Proceedings of the National Academy of Sciences of   the United States of America (1973) 70(11), 3240–3244.
  3. Ramírez, J.L. y Dawid, I.B. Mapping of mitochondrial DNA in Xenopus laevis and Xenopus borealis. J. Mol. Biol. (1978). 119,133-146.
  4. Ohi, S., Ramírez, J.L. y Dawid, I.B. Mapping of Mitochondria 4S RNA genes by electron microscopy. J. Mol. Biol. (1978) 121: 299-310.
  5. Premoli de Percoco, G., Galindo, I., y Ramírez, J.L. In situ hybridization with digoxigeninlabelled DNA probes for the detection of human papillomavirus-induced focal epithelial hyperplasia among Venezuelans Virchows Archiv-A Pathol. Anat. (1992) 420:295-300.
  6. Premoli de Percoco, G., Galindo, I., Ramírez, J.L., Perrone, M. y Rivera, H. Detection of human papillomavirus-related oral verruca vulgaris among venezuelans. J. Oral Pathol. Med. (1993) 22:113-116.
  7. Premoli de Percoco, Pinto-Cisternas, J., Ramírez, J.L. y Galindo, I. Focal Epithelial Hyperplasia: HPV virus-induced disease with a genetic predisposition in a Venezuelan family. Hum. Genet. (1993) 91:386-388.
  8. Toro, F.I., Ramírez, J.L., Bianco, N. y Machado, I.V. Técnicas de Biología Molecular para la detección del Virus de Hepatitis Delta I: Obtención de la sonda diagnóstica específica. GEN (1989).43:177-181.
  9. Urdaneta, L., Guevara, P. and Ramirez, J.L. Evaluation of DNA Recombinant Methodologies for the Diagnosis of Plasmodium. falciparum and their Comparison with the Microscopy Assay. Mem. Inst. Oswaldo cruz (1998) 93:639-646.
  10. Ramírez, J.L. y Guevara, P. The ribosomal gene spacer as a tool in the taxonomy of Leishmania. Mol. Biochem. Parasitol. (1987) 22:177-183.
  11. Guevara, P., Alonso, G., Da Silveira, J.F., De Mello, M., Scorza, J.V., Añez, N. y Ramírez, J.L. Identification of New World Leishmania using ribosomal gene spacer probes. Mol. Biochem. Parasitol. (1992) 56:15-26.
  12. Guevara, P., Rojas, E., González, N., Scorza, J.V., Añez, N., Valera, M. and Ramírez, J.L. Presence of Leishmania braziliensis in blood samples from cured patients or at different stages of immunotherapy. Clin. Diag. Lab. Immunol. (1994) 1:385-389.
  13. Delgado, O, Guevara, P., Silva, S., Belfort, E y Ramírez, J.L. Follow-up of a human accidental infection by Leishmania (V) braziliensis, using conventional immunological techniques and PCR. Am. J. Trop. Med. Hyg. (1996) 55:267-272
  14. Ramírez, J. L., Galindo, I., Guevara, P., Da Silveira, J. F., Novak, E., González, N., Añez, N. y Scorza, J. V. Detection and identification of Chagas' disease agent Trypanosoma cruzi, using nonradioactive genetic probes. Annals of XVII World Congress of Anatomical and Clinical Pathology Ed. G.G Santoscoy , Monduzzi Editore (1993). pp 13-16.
  15. González, N., Galindo, I., Guevara, P., Novak, E., Scorza, J.V., Añez, N., da Silveira, J.F. and Ramírez, J.L. Identification and detection of Trypanosoma cruzi by using a DNA amplification fingerprint obtained from the ribosomal intergenic spacer. J. Clin. Microbiol. (1994) 2:153-158.
  16. Blassini, A.M., Delgado, M.B., Valdivieso, C., Guevara, P., Ramírez, J.L., Stekman, I.L., Williams, R.C. y Rodríguez, M.A. Restriction fragment length polymorphisms of constant region genes of immunoglobulin lambda chains in Venezuelan patients with systemic lupus erythematosus. Lupus (1996) 55:267-272.
  17. Chiurillo, M. A., Moran, Y., Cañas, M., Valderrama E., Granda N., Sayegh, M., Ramírez J. L. Ramírez J. L. Genotyping of Helicobacter pylori virulence associated genes shows high diversity of strains infecting patients in Western Venezuela. International J. of Infec. Dis.. (2013) 17(9): e750-6.
  18. Torres, Keila; Valderrama, E., Sayegh, M., Ramirez, J. L., y Chiurillo, M A. Study of the oipA genetic diversity and EPIYA motif patterns in cagA-positive Helicobacter pylori strains from Venezuelan patients with chronic gastritis. Microbial Pathogenesis. (2014) 76:26-32.
  19. Galindo, I., Rangel-Aldao, R. y Ramírez, J.L. A combined PCR-colour development reaction hybridisation assay in a microtiter format for the detection of Clostridium spp. Appl. Microbiol. Biotechnol. (1993) 39:553-557.
  20. Guevara, P., Ramírez, J.L., Elina Rojas, Jose V. Scorza, Nestor González y Nestor Añez PCR detection of Leishmania braziliensis in blood samples 30 years after spontaneous cure. Lancet (1993) 341:1341.
  21. Ramírez, J.L. y Guevara, P. () Persistent infection by Leishmania (V) braziliensis Memorias do Instituto Oswaldo Cruz (1997) 92:333-338.
  22. Añez, N., Carrasco H., Parada, H., Crisante, G., Rojas, A., Fuenmayor, C., Gonzalez, N., Percoco, G., Borges, R., Guevara, P. and Ramirez, J.L. Myocardial parasite persistence in chronic chagasi patients. Am. J. Trop. Med. Hyg. (1999) 60:726-732.
  23. Chiurillo, M.A, Beck, A.E., Devos, T., Myler, P.J., Stuart, K. y Ramirez, J.L. Cloning and Characterization of Leishmania donovani telomeres. Exp. Parasitol. (2000) 94:248-258.
  24. Chiurillo, M.A., Santos, M.R. M., Franco Da Silveira, J. y Ramírez, J.L. An improved general approach for cloning and characterizing telomeres: the protozoan parasite Trypanosoma cruzi as model organism. Gene (2002) 294:197-204.
  25. Kim, D., Chiurillo, M. A., El-Sayed, N. Jones, K., Santos, M.R.M., Cerda,P.P. Andersson, B., Myler, P., Franco da Silveira, J. y Ramírez, J.L. Telomere and subtelomere of Trypanosoma cruzi chromosomes are enriched in (pseudo)genes of retrotransposon hot spot and transialidase-like gene families: the origins of T. cruzi telomeres. Gene (2005) 346:153-161.
  26. Moraes Barros, R.R., Marini,M.M., Antônio,C.R., Cortez,C.R., Miyake, A.M., Lima, F.M., Ruiz, J.C., Bartholomeu, D.C., Chiurillo, M. A, Ramirez, J.L. y Franco da Silveira, J. Anatomy and evolution of telomeric and Subtelomeric regions in the human protozoan parasite Trypanosoma cruzi. BMC0 Genomics (2012) 13:229.
  27. El -Sayed, Najib et al. The genome sequence of Trypanosoma cruzi, etiological agent of Chagas’ disease. Science (2005) 309:410-415.
  28. Ramirez, J.L. y Holmes, D. The need for genomics networking in Latin America, SciDev.Net http://www.scidev.net/ Agosto 14 (2003).
  29. Ramírez, J.L. Biosafety why and for whom?, Latin America on target. Interciencia (2003) 669-672.
  30. Ramírez, J.L., Santana, M.A y Galindo-Castro, I. The role of Biotechnology in art preservation. Trends in Biotech. (2005) 23:584-588
  31. Pineda Bernal, L, Borjas, L., Zabala, W, Tovar, F., Portillo, M.G., Lander N., Fernández, E., Chiurillo, M.A., Ramírez, J.L. Genetic variation of 15 STR autosomal loci in the Maracaibo population from Venezuela. Forens. Sci. Int. (2006) 161:60-63.
  32. Lander, N., Rojas, M.G., Chiurillo, M.A., y Ramírez, J.L. Haplotype diversity in Human mitochondrial DNA hypervariable regions I, II and III in the city of Caracas (Venezuela). Forens. Sci. Int. Genetics (2008). 2 e61–e64.
  33. Campelo, R., Galindo, M.M., Ramirez, J.L. Charaterization of Trypanosoma cruzi Telomerase. Acta Tropica (2011) 120:171-178.
  34. Galindo M.M., A, Rodriguez, E., Rojas, M.G., Figarella, K., Campelo, R., y Ramírez, J.L. Heat-activated and Thermo-resistant Telomerase Activity in Leishmania major Friedlin. Acta Tropica (2009) 111:86-89.
  35. Riward Campelo, Isabel Díaz Lozano, Katherine Figarella, Antonio Osuna and José Luis Ramírez, Leishmania major telomerase TERT protein has a nuclear mitochondrialeclipsed distribution that is affected by oxidative stress. (2015) Infect. Immunity 83:57-66.
  36. Florez I, Pirrone I, Casique L, et al. Independent origin for m.3243A>G mitochondrial mutation in three Venezuelan cases of MELAS syndrome Clin Biochem. (2022) S00099120(22)00221-1.
  37. Casique L, De Lucca M, Mahfoud A, Luis Ramírez J. (2022) MELAS a clinically and genetically heterogeneous syndrome. Clin Biochem. (2022) Nov:S0009- 9120(22)002442.
Ensayo
Referencias

NOTA: Toda la información que se brinda en este artículo es de carácter investigativo y con fines académicos y de actualización para estudiantes y profesionales de la salud. En ningún caso es de carácter general ni sustituye el asesoramiento de un médico. Ante cualquier duda que pueda tener sobre su estado de salud, consulte con su médico o especialista.