Asociación Venezolana para el Avance de la Ciencia
COVID-19 and the heart: An update for clinicians
Fecha de recepción: 19/04/2020
Fecha de aceptación:
29/05/2020
Abstract
SARS-CoV-2, the cause of the COVID-19 pandemic has significantly impacted cardiovascular
healthcare. Patients with pre-existing cardiovascular disease are at higher
risk of morbidity and mortality. The virus may affect the heart directly and indirectly
with clinical syndromes of acute myocardial injury, myocarditis, acute coronary syndromes,
heart failure, arrhythmias, and venous thromboembolism. Some therapeutics
under investigation for COVID-19 may also have adverse cardiac effects. The
involvement of the RAAS system in viral entry makes it pertinent to consider the
effects of medications that modulate the system. Comprehensive knowledge of
peculiar cardiovascular manifestations of COVID-19 and the role of RAAS in the
prognosis of COVID-19 disease is needed for optimal patient management.
Key Word
acute myocardial injury, COVID-19, myocaritis, NSAID, RAAS
COVID-19 and the heart: An update for clinicians
Ahmed Goha1,2 | Kenechukwu Mezue2,3 | Paul Edwards2 | Felix Nunura2 | Dainia Baugh2 | Ernest Madu2
1Aga Khan University Hospital, Nairobi, Kenya
2Heart Institute of the Caribbean and HIC Heart Hospital, Kingston, Jamaica
3Department of Hospital Medicine, Altru Health System, Grand Forks, North Dakota
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