Agosto-Octubre 2000 5
ISSN 1317-987X
 
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Virología
El calcio y el rotavirus

Bibliografía

  • Ruiz MC, Charpilienne A, Liprandi F, Gajardo R, Michelangeli F, Cohen J. The concentration of Ca2+ that solubilizes outer capsid proteins from rotavirus particles is dependent on the strain. J Virol 1996;70(8):4877-83.
  • Dormitzer PR, Greenberg HB. Calcium chelation induces a conformational change in recombinant herpes simplex virus-1-expressed rotavirus VP7. Virology 1992;189:828-832
  • Gajardo R, Vende P, Poncet D, Cohen J. Two proline residues are essential in the calcium-binding activity of rotavirus VP7 outer capsid protein. J Virol 1997;71(3):2211-6.
  • Clark SM, Roth JR, Clark L, Barnett BB, Spendlove RS. Trypsin enhancement of rotavirus infectivity:mechanism of enhancement. J.Virol. 1981;39:816-822
  • Zarate S, Espinosa R, Romero P, Mendez E, Arias CF, Lopez S. The VP5 domain of VP4 can mediate attachment of rotaviruses to cells. J Virol 2000;74(2):593-9.
  • Zarate S, Espinosa R, Romero P, Mendez E, Arias CF, Lopez S. The VP5 domain of VP4 can mediate attachment of rotaviruses to cells. J Virol 2000;74(2):593-9
  • Coulson BS, Londrigan SL, Lee DJ. Rotavirus contains integrin ligand sequences and a disintegrin-like domain that are implicated in virus entry into cells. Proc Natl Acad Sci U S A 1997;94(10):5389-94
  • Hewish MJ, Takada Y, Coulson BS. Integrins alpha2beta1 and alpha4beta1 can mediate SA11 rotavirus attachment and entry into cells. J Virol 2000;74(1):228-36.
  • Superti F, Donelli G. Gangliosides as binding sites in SA-11 rotavirus infection of LLC-MK2 cells. J.Gen.Virol. 1991;72:2467-2474.
  • Martinez CG, Guinea R, Benavente J, Carrasco L. The entry of reovirus into l cells is dependent on vacuolar proton-ATPase activity. J.Virol. 1996;70:576-579
  • Perez L, Carrasco L. Involvement of the vacuolar H(+)-ATPase in animal virus entry. J.Gen.Virol. 1994;75:2595-2606.
  • Guinea R, Carrasco L. Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cells. J.Virol. 1995;69:2306-2312.
  • Keljo DJ, Kuhn M, Smith A. Acidification of endosomes is not important for the entry of rotavirus into the cell. J Pediatr Gastroenterol Nutr 1988;7(2):257-63.
  • Ludert JE, Michelangeli F, Gil F, Liprandi F, Esparza J. Penetration and uncoating of rotaviruses in cultured cells. Intervirology 1987;27:95-101.
  • Ruiz MC, Abad MJ, Charpilienne A, Cohen J, Michelangeli F. Cell lines susceptible to infection are permeabilized by cleaved and solubilized outer layer proteins of rotavirus. J Gen Virol 1997;78(Pt 11):2883-93.
  • Ruiz MC, Alonso Torre SR, Charpilienne A, Vasseur M, Michelangeli F, Cohen J, et al. Rotavirus interaction with isolated membrane vesicles. J.Virol. 1994;68:4009-4016
  • Cohen J, Laporte J, Charpilienne A, Scherrer R. Activation of rotavirus RNA polymerase by calcium chelation. Arch.Virol. 1979;60:177-186.
  • Au KS, Chan WK, Burns JW, Estes MK. Receptor activity of rotavirus nonstructural glycoprotein NS28. J.Virol. 1989;63:4553-4562.
  • Meyer JC, Bergmann CC, Bellamy AR. Interaction of rotavirus cores with the nonstructural glycoprotein NS28. Virology 1989;171(1):98-107.
  • Michelangeli F, Liprandi F, Chemello ME, Ciarlet M, Ruiz MC. Selective depletion of stored calcium by thapsigargin blocks rotavirus maturation
  • But not the cytopathic effect. J Virol 1995;69(6):3838-47
  • Poruchynsky MS, Maass DR, Atkinson PH. Calcium depletion blocks the maturation of rotavirus by altering the oligomerization of virus-encoded proteins in the ER. J.Cell Biol. 1991;114:651-656.
  • Mirazimi A, Nilsson M, Svensson L. The molecular chaperone calnexin interacts with the NSP4 enterotoxin of rotavirus in vivo and in vitro. J Virol 1998;72(11):8705-9.
  • Michelangeli F, Ruiz MC, del Castillo JR, Ludert JE, Liprandi F. Effect of rotavirus infection on intracellular calcium homeostasis in cultured cells. Virology 1991;181:520-527.
  • Del Castillo JR, Ludert JE, Sanchez A, Ruiz MC, Michelangeli F, Liprandi F. Rotavirus infection alters Na+ and K+ homeostasis in MA-104 cells. J.Gen.Virol. 1991;72:541-547.
  • Perez JF, Chemello ME, Liprandi F, Ruiz MC, Michelangeli F. Oncosis in MA104 cells is induced by rotavirus infection through an increase in intracellular Ca2+ concentration. Virology 1998;252(1):17-27.
  • Newton K, Meyer JC, Bellamy AR, Taylor JA. Rotavirus nonstructural glycoprotein NSP4 alters plasma membrane permeability in mammalian cells. J Virol 1997;71(12):9458-65
  • Ball JM, Tian P, Zeng CQ, Morris AP, Estes MK. Age-dependent diarrhea induced by a rotaviral nonstructural glycoprotein. Science 1996;272(5258):101-4.
  • Morris AP, Scott JK, Ball JM, Zeng CQ, O'Neal WK, Estes MK. NSP4 elicits age-dependent diarrhea and Ca(2+)mediated I(-) influx into intestinal crypts of CF mice. Am J Physiol 1999;277(2 Pt 1):G431-G444.
Introducción
La estructura de la cápside del rotavirus es dependiente de Ca2+
Un modelo de entrada del rotavirus en la célula
Su ciclo intracelular requiere diferentes ambientes de Ca2+
Infección viral y homeostasis de Ca2+
La diarrea inducida por el rotavirus
Conclusión
Bibliografía

NOTA: Toda la información que se brinda en este artículo es de carácter investigativo y con fines académicos y de actualización para estudiantes y profesionales de la salud. En ningún caso es de carácter general ni sustituye el asesoramiento de un médico. Ante cualquier duda que pueda tener sobre su estado de salud, consulte con su médico o especialista.





Instituto de Medicina Tropical - Facultad de Medicina - Universidad Central de Venezuela.
Elaborado por el Centro de Análisis de Imágenes Biomédicas Computarizadas CAIBCO,
caibco@ucv.ve
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