The authors are not aware of any affiliations, memberships, funding, or financial holdings that might be perceived as affecting the objectivity of this review.

Authors’ contributions

C.A.F.A., M.J.A., I.L.B and R.F.R. participated in selection and reviewing of cited literature. C.A.F.A. aimed and wrote the preliminary version of this manuscript, designed tables, performed art-work of figures, and performed the in silico analysis for miRNA target and RNA hybridization prediction. F.A.P.U. did the staining technique for figure 1. C.A.F.A., R.F.R., and F.A.P.U. implemented cell culture techniques for figure 3. C.A.F.A, R.F.R, F.A.P.U, R.G.A, M.J.A, I.L.B read, drafted, discussed and approved the final version of this manuscript.

Acknowledgments